Posted by bleauberry on August 10, 2012, at 16:15:41
In reply to Least cognitive impairing/emotionally numbing SSRI, posted by underthesky on August 9, 2012, at 17:18:16
Throughout literature and in my own experience, I think prozac is the least numbing. But, they all cause the numbing. Prozac maybe not as bad, but it's still there.
More important than the actual med, maybe, is the size of the dose. If one needs to take a dose for their depression that is high enough to cause numbing, then like it or not there will have to be another substance in the mix to counterbalance all that extra serotonin. It's all the flooding or serotonin without attention to other neurotransmitters that causes numbing and all sorts of other problems, in my opinion anyway.
To fit your desires however, there are 3 good alternatives to choose from to add to your ssri, which ever one you decide on, and they are not meds. Rhodiola rosea, or tyrosine, or dlpa. Any of those can not only prevent/reverse the numbing, but also make the whole antidepressant response more robust, and without any more meds. I might have had some ideas on other meds but you said you weren't interested in those, and thus the above suggestions instead, which actually can work better than any meds anyway.