Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: D2 (D3) agonists' capacity to flatten affect » SLS

Posted by psychobot5000 on June 28, 2012, at 18:46:48

In reply to Re: D2 (D3) agonists' capacity to flatten affect » psychobot5000, posted by SLS on June 28, 2012, at 14:07:16

> > I am unsure whether there might be a dosing regimen of agents with D3 (a 'D2-like' receptor) that might prevent or supercede this phenomenon, i.e. perhaps with higher doses.
>
> Very possibly. The dosage-response curve of apomorphine, comprising sedation followed by hyperlocomotion, is an example of this.
>
> Aripiprazole and cariprazine are partial D2/D3 agonists that seem not to have a pervasive effect of the flattening of mood at low dosages. Infrequently, these drugs can blunt cognition and affect at high dosages.
>
>
> - Scott

Hmm. This is useful--though aripiprazole unfortunately blunted my cognition in a big way even on a small dose. ...I've heard of that effect wearing off, though.

Do you know of any links/papers that might support these ideas, Scott, i.e. something I could take to my doc to show there's good reason to do a trial?
-PB


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:psychobot5000 thread:1019496
URL: http://www.dr-bob.org/babble/20120608/msgs/1020364.html