Posted by bleauberry on June 14, 2012, at 15:47:03
In reply to cymbalta and another SNRI, posted by b2chica on June 12, 2012, at 15:40:27
The mix you suggested doesn't sound good to me. I could spend some time explaining why.
Here are similar ones that HAVE already been done with good results: (using effexor not pristiq, but they are similar enough I think to make inferences).
Effexor + Savella
Cymbalta + Savella
Effexor + Wellbutrin + Savella
Effexor + Wellbutrin
And as SLS mentioned, Nortriptyline is a strong worthy player too. I'm not a big fan of wellbutrin so my biased preference would be savella first try, nortriptyline second try, wellbutrin last.