Posted by bleauberry on June 14, 2012, at 15:00:13
In reply to Olanzapine '7653', posted by HappyGirl on June 13, 2012, at 10:49:25
Well I'm sorry but I guess we can add you to the list of babblers who have reported similar generic experiences over the last few years. I've noted dramatic differences myself in many, but not all, experiences with generics. Generic A is not the same as Generic B and I don't care how hard some pinhead scinetific white coat geek tries to convince me otherwise.
There has been some research on this but not much. The ways they did the testing were flawed and not very helpful in either supporting the case or refuting it.
Mere casual observation tells me this is a real problem that has been spontaneously noticed by many even when they had no prior warning or awareness.
I'm not a molecular scientist so I couldn't tell you why two supposedly identical substances made from different sources could behave differently in the human body. But they do. I do know from some experience with custom dose making and LDN that different fillers do make a big difference. You can actually change the absorption rate and process with the wrong filler ingredient. The results of that could vary as far the human imagination can go. The word "neutral" when referring to fillers has not been thoroughly examined I don't think.
With LDN rapid absorption is needed. The wrong filler will slow down the absorption just enough to destroy the entire premise of taking LDN in the first place. I don't think it is a stretch to envision other adverse events happening because of a wrong filler choice.
My Lyme doc insisted on brand. He would later try to switch to generic but usually they had to go back to brand. He had too many failures starting with generics. He said some generics are better than others and that when one works, stay with that exact one. He said one of the pain meds is actually better as a generic than brand.. So it can go both ways. I've always felt that if someone starts a new med, it happens to be generic, and they do not have a good trial with that med, that unless they try the brand version before abandoning that med altogether they really haven't even tried that med at all. It can be that much of a difference.
I'm sure debates and hypothesis will fly for years to come on this topic. But for now what matters is that you get back on the med that worked good for you. You will probably have to do some searching on the phone and on the web to find out who near you can get that particular generic you like or already has it in stock. Your pharmacy maybe changed who they buy the generic from, but some other pharmacy still has it or can get it. Actually I think most pharmacies can special order the one of your choice if they don't regularly carry it, because I did that with Nortriptyline....one generic was better than another and was better than brand....actually that one generic was the only one that felt any good at all and the other two felt more like crap.