Posted by novelagent on June 13, 2012, at 17:05:50
In reply to Re: SLS.. An awsome xenobiologic that U DONT KNOW ABOU » michaelskytree, posted by SLS on June 6, 2012, at 18:47:53
I doubt these atypicals coming up are going to do much more than be a me-too next to Latuda. I would dump Abilify and go with Latuda-- I got weight gain from Zyprexa, but Latuda didn't give me any weight gain, and after switching over to Latuda from Risperdal, my blood work was perfect (on Risperdal, I had elevated prolactin levels).
I would switch to Latuda, maybe add Aricept. Aricept boosted my mood and cognition when I was on it. I'm going to go back on it. I thought it caused hypomania, but I think I was being too liberal with that word, especially since it didn't cause any hypomanic symptoms as long as I took my klonopin (1mg 3x/day). It's a fine drug, Aricept.
The research for Latuda is very solid. It's the only antipsychotic on the market with a robust body of evidence demonstrating it helps cognition, or at least doesn't dampen cognition, in head-to-head studies. A lot of research on this, especially for a new drug.
> Keep an eye out for a drug called cariprazine. It is the second in a series of DA D2/D3 receptor partial agonists like Abilify. I will probably ask my doctor to allow me to crossover to cariprazine from Abilify in an attempt to avoid weight-gain and elevated triglycerides. Perhaps it will be a cleaner drug with respect to cognition and memory. It may not be, but I would regret it if I weren't to give cariprazine a try. It is currently in phase III investigation, and is due to be approved within a year.
> - Scott