Posted by g_g_g_unit on June 4, 2012, at 23:38:19
In reply to Re: not sure what to do, posted by Willful on June 4, 2012, at 10:44:35
> What does your pdoc say?
> I had various reactions to parnate, at lower doses, one of which was to feel incredibly tired. This was the reaction my pdoc focussed on, and for that he raised the dose. Parnate causes a lot of sleep disturbances and in my case this got pretty extreme although the tiredness somewhat resolved (not entirely but enough for me to function) at higher doses.
> I had continuous, strange, highly repetitive dreams which responded to a higher dose but that over time was eclipsed by a state of blunted emotion. Over time, I felt disconnected from emotions and while I could reason well, my conclusions never felt as clear as they normally would. Maybe it was more an underlying exhaustion from the years of not sleeping, and the emotional drain of the particular dream I was having. So I have mixed feelings about parnate, which lean toward the negative. But still, a lot of people get help from it.
Interesting .. yeah, I find it emotionally blunting too (which is the opposite of what I was hoping for..). I don't dream though, unless I take Klonopin.
> All in all, I would consult with your pdoc about whether higher doses of parnate might help, but I would be cautious about going too high. People say they do 120mg and such, but imo that's an awful lot. I was at 100mg and while I never had any food issues (I was quite vigilant, but occasionally ate something without thinking), the dose probably caused the mental issues. Emsam does causes agitation, although a different one from parnate, but that also has been mitigated over time. I would stick with the parnate for a while longer, but I guess after two and a half weeks or three weeks, I would be discouraged.
My psychiatrist wouldn't prescribe more than 60mg anyway. The maximum recommended dose here is 30mg, but I managed to convince him to follow the American guidelines, because I know a Harvard psychiatrist who regularly prescribes 60mg for OCD patients. I have read about people in Australia taking more than that, though.
I personally wonder if it isn't some kind of imbalance between MAO-inhibition and the stimulant effect .. 10/20mg caused a similar agitation, which eased up on 30mg (but didn't help mood, anxiety) .. so maybe 60/70mg will provide the right balance.
> I don't have OCD though, and I"m sure that complicates your treatment. I'm much more reluctant than many here to attribute my reactions on any day to a drug per se-- because it's really impossible to know without a doubt how you would react. Unless you're never angry, characterologially, I wouldn't necessarily attribute the angry thoughts to the drug. But you should also trust your own instincts-- while also taking account of your pdoc's recommendations-- in making a decision about how long to test out the potential that parnate might have.
No, you're correct. I harbor a tremendous amount of anger towards my family, and that's generally who the thoughts are directed towards. What is more strange is the thoughts' persistence (i.e. I will have angry, intrusive monologues throughout the day, ruminate obsessively over past hurts etc.). My litmus tends is when I tend to feel angry towards people I otherwise like -- like my psychiatrist -- and that's been occurring too, which makes me think it's just a general dysphoria from overstimulation. I also feel more inclined to isolate and not want to be around friends (another litmus test).