Posted by g_g_g_unit on May 31, 2012, at 4:45:17
I went up to 50mg of Parnate three days ago and am getting this relatively uncomfortable 'wired' sensation. It feels like excess noradrenergic activity and leaves me feeling kind of numb, blank-minded and interferes with the fluidity of my reading, for example (i.e. my focus becomes very choppy). Taking like 1/6 of a 0.5mg Klonopin tab (hey -- I'm sensitive) resolves the problem, but obviously isn't a long term solution.
I know there's some catch up that occurs between the stimulant and MAO-inhibiting effects, so should I wait it out a bit?
One good sign (per Dr. Gilman's formulation) is that my blood pressure has finally dropped to a noticeable degree, so I thought it might mean I was in fact hitting upon a therapeutic dose.