Posted by g_g_g_unit on May 25, 2012, at 7:49:06
In reply to Re: update for SLS » g_g_g_unit, posted by SLS on May 25, 2012, at 6:18:00
> I have always been under the impression that temazepam is relatively ineffective for sleep initiation, but good for sleep maintenance. So, if you are disappointed in its efficacy, that would argue for trying Sonata, Ambien, or Ativan. I would still give temazepam a try first. You never know how you will react to it. It might be the perfect drug for you. It should produce very little if any hangover effect the next day. It has no active metabolites.
I suggested Ambien, but he said he doesn't like mixing sleep-aids of differing classes (i.e. Z-drugs with benzodiazepines).
> Parnate and memantine (Namenda): I have seen it written in many places on the Internet that memantine prevents tolerance to psychostimulants. However, I have never seen it for myself, and I don't recall seeing and scientific articles that reports memantine as being effective in this capacity. Memantine itself has been reported to help with ADHD and might potentiate stimulants (as opposed to preventing tolerance). Either way, it is not unreasonable to try memantine.
From what I understand, it definitely attenuates tolerance, rather than simply potentiating stimulants, since certain early, transient effects (increased sociability, mood boost, etc.) seem to persist with treatment. I can't provide any proof though; only subjective accounts.
Since people confuse the stimulating effect with an anti-depressant effect in Parnate, I thought that preventing tolerance to the stimulant effect might cause some confusion in me about whether it was genuinely working. That said, I've also e-mailed a) a neuropsychiatric centre, and b) two OCD specialists, and none use Memantine off-label for OCD (my personal psychiatrist won't prescribe it, but will refer to someone who does). This country is kind of ridiculous in my opinion.
Do you find Parnate itself helpful for anhedonia? Lately, my moods have been feeling quite dark and grey, but I know one poster here (Serge) said that would happen to him until he hit 60mg.
> If necessary, amphetamine or methylphenidate can be added to Parnate to treat the ADHD.
I'm not aware of any psychiatrist in my state who would prescribe Parnate with a stimulant. I've given up on that idea.