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Re: Requip for SSRI induced sexual disfunction

Posted by Novelagent on May 7, 2012, at 6:43:40

In reply to Requip for SSRI induced sexual disfunction, posted by Laney on May 1, 2012, at 19:52:07

This is taken from a user group post by someone else:

Background about me: I'm a 27 year old male. I was put on Paxil for social
anxiety disorder. After a few months, I found it really hard to orgasm. I was
having marathon sex sessions with my wife. I went off the Paxil in March of 2009
(after a total of 8 months on it) and since then I've noticed that it takes me
forever to get aroused. I've also been hit with extreme premature ejaculation,
loss of libido and interest in sex.

After trying a few products mentioned by people here that didn't work, I decided
to look at the matter scientifically. PSSD is most likely caused by persistent
desensitization of 5-HT1A receptors. After doing some research on substances
that reverse desensitization of these receptors I stumbled across inositol, a
naturally occuring sugar in our bodies.

I've been on 18 grams of inositol once daily at bedtime for the past 7 weeks and
few days (Jan 24/2011 to March 16/2011) and I am happy to say that my interest
in sex has returned, my erections are back to normal, and my premature
ejaculation has returned to how it was before I went on Paxil. Never will I
touch an SSRI again.

I hope this will help anyone who is still trying to get rid of this horrible

> I have been looking up requip for my mom and dad who both have restless leg syndrome and thought I'd post this old post about it because it's supposed to help with SSRI induced sexual disfunction.
> The below was posted on Babble November 22, 2004
> "I have never heard of requip. But I did a quick search and came up with this article that I pasted below" Posted by PHOENIX GIRL
> With the SSRI's and SNRI's have a generally favorable side effect profile, their administration can be associated with adverse sexual effects in a third or more of treated patients. Antidepressant-induced sexual side effects can cause marked patient distress and their effective treatment can significantly improve patient compliance.
> A variety of strategies include adjunctive sildenafil (Viagra) buspirone, ginkgo biloba as well as dopaminergic agents like bupropion (Wellbutrin) and methylphenidate, have been reported helpful for the treatment of antidepressant-induced sexual dysfunction. Our group has recently reported positive experience with the use of the dopaminergic agonist ropinirole (Requip) for the treatment of SSRI-induced sexual dysfunction (Worthington, et al 2001).
> Treatment was generally initiated at 0.25 mg qd and titrated up by 0.25-0.5 mg q 4-7 days targeting doses of 1-4 mg/d given bid. Improvement was noted in about half the patients on a variety of parameters of sexual functioning including libido, erection and orgasm in both men and women. The agent was generally well tolerated in this dose range with the most common side effects being sedation, dizziness and GI distress. Doses greater than 8 mg/d have been associated with sudden episodes of marked sleepiness requiring caution in those operating motor vehicles. Response generally occurred within the first 2 - 4 weeks of treatment.
> Ropinirole, as well as a related compound, pramizpexole (Mirapex) are D-2 agonists indicated for the adjunctive treatment of Parkinson's Disease. Although not well studied, these agents have been used in psychiatry to reduce cocaine craving and adjunctively with SSRI's for refractory depression. It appears that they represent another potentially useful addition to the list of agents that may help reverse antidepressant induced sexual dysfunction.
> from:
> > My doctor just prescribed this parkinson's drug for my antidepressant-induced sexual side effects.




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