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Muscle tension / spasm? / knots from SSRI/SNRIs

Posted by displaced9 on March 4, 2012, at 7:12:37

Hi All,

I had posted on here about about constant muscle tension/spasms/pain whilst taking Zoloft. I read that this is a rare side effect of Zoloft and thus slowly discontinued the Zoloft (from a dosage of 300mg/daily) down to 0. I then switched over to Remeron (Mirtazapine) going to a dose of 90 mg/daily. At this dose, I had substantial weight gain in a short time, and my anxiety was kind of "through the roof" although the muscle tension had gone away. After trying to stick out the Remeron for 2+ months, we decided to decrease the dose (and discontinue) and cross-over to Effexor XR. I now take Effexor XR 225mg/daily plus Wellbutrin XL 300mg/daily, and unfortunately my muscle tension is back. While not as bad as before, it can get pretty uncomfortable. I can only attribute this to either the Effexor or not taking the Remeron, since the WB was added well after I started Effexor and the muscle tension came back.

I know that muscle tension / pain can be a sign of serotonin syndrome, but I have no other symptoms. In fact, I feel pretty fantastic with Effexor. My anxiety is under control and I am much more calm.

Is it / could it be a side effect of anything that affects Serotonin to cause this muscle tension?

I can take a Rx muscle relaxer but I don't want to rely on that. I bought Glycine and GABA last night as I read that can help, but wanted to get input on the muscle tension/pain.

It is mostly my upper back/neck/shoulders but I can also feel the tension in my arms, legs, etc.


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poster:displaced9 thread:1012353
URL: http://www.dr-bob.org/babble/20120302/msgs/1012353.html