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Re: Depakote questions » SLS

Posted by ed_uk2010 on February 18, 2012, at 13:21:23

In reply to Re: Depakote questions » ed_uk2010, posted by SLS on February 17, 2012, at 15:13:23

>Do you know what the mechanism is behind the production of insomnia by valproate? Could it be some sort of physiological disinhibition?

I'm not sure of the mechanism, but it does seem to be a problem.

http://www.ncbi.nlm.nih.gov/pubmed/22315172

'VPA....can increase awakening and arousal. VPA can increase wake time after sleep onset.'

 

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URL: http://www.dr-bob.org/babble/20120212/msgs/1010660.html