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Re: One more thing.. » SLS

Posted by tensor on February 5, 2012, at 9:10:58

In reply to Re: One more thing.. » Zyprexa, posted by SLS on February 5, 2012, at 5:47:17

> > yes I took zyprexa and abilify at the same time for a while, then stoped the abilify. I went cold turky off abilify and suffered a major withdraw stage where I needed a higher dose of zyprexa for a while, a much higher dose, 30-50mg.
>
> That's interesting. Abilify is much more potent than Zyprexa at binding to the D2 receptor. Perhaps there was a supersensitivity thing going on there. Unlike Zyprexa, Abilify also binds to the D3 receptor. Any withdrawal effects coming from this would probably not be counteracted by Zyprexa.

I thought Zyprexa binds to D1-D4.
http://www.psychiatrist.com/pcc/pccpdf/v05s03/v05s0302.pdf
http://www.psychresidentonline.com/atypical%20antipsychotics.htm
http://ajp.psychiatryonline.org/article.aspx?articleid=175102

> These are just musings. I make no claim as to the validity of any of my theories.

Got it. :)


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