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Re: how possible is it to have DBS done » poser938

Posted by SLS on January 10, 2012, at 7:28:09

In reply to how possible is it to have DBS done, posted by poser938 on January 10, 2012, at 0:40:42

> since it isnt approved by the FDA for depression, how possible is it for someone to have this therapy?
> im about to be having rTMS done, and am hoping it works for me.. but i like to pan ahead just in case it doesnt work for me. medication isnt really an option for me anymore because because 90% of the time when i take a med and it ha its effect on me, whether bad or good, it is permanent. my brain doesnt see the need to go back to normal after stopping a med.. and it has truly ruined my life. but like i said, if rTMS doesnt work for me, is it next to impossible to have DBS done? do you just have to be lucky to participate in a trial for it? i am very suicidal and just need something to help me feel better.

You can try contacting:

http://wwwp.medtronic.com/Newsroom/NewsReleaseDetails.do?itemId=1235065362795&lang=en_US

I hope the rTMS works for you. 5 days per week?

Twinleaf has had success with rTMS. Perhaps you can ask him/her more about it.

DBS. I am still afraid of it. However, I was fast approaching a decision to try it. I was down to my last drug. I had a feeling that my brain's Brodmann Area 25 was hyperactive. That's what DBS is meant to treat. DBS really is not a nerve stimulator. It is a nerve blocker.

I am having success treating my depression with an old antihypertensive drug called prazosin. It crosses the BBB readily and makes its way into the brain, where it blocks NE alpha-1 receptors.

It occurred to me that prazosin might quiet those neurons that are observed to be hyperactive in cingulate cortex (Brodmann areas 24, 25) in indviduals with MDD. If so, it would effectively mimic DBS. This is a wild guess on my part.

Personal question, I know: Were you physically or emotionally abused as a child? What about parental neglect? PTSD? These are some of the things that prazosin might be able to treat. I am still trying to characterize what types of depression prazosin might be an effective treatment for. It is certainly safe enough.

I cannot yet recommend prazosin to anyone, but it would be a quick 4 week trial. Perhaps it makes sense to look into prazosin before going with DBS.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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