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Re: Adding Parnate and prazosin. - Cingulate

Posted by SLS on January 5, 2012, at 4:16:13

In reply to Re: Adding Parnate and prazosin., posted by sigismund on January 5, 2012, at 3:44:08

Subject: NE alpha-1 receptors in cingulate.

It occurred to me that prazosin might quiet those neurons that are observed to be hyperactive in cingulate cortex (Brodmann areas 24, 25) in indviduals with MDD. If so, it would effectively mimic DBS.

This is a wild guess for which I have little supportive evidence.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1005781
URL: http://www.dr-bob.org/babble/20111226/msgs/1006388.html