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Re: Fluanxol (flupenthixol) for Bipolar ??? » X-ray

Posted by NKP on April 10, 2011, at 13:47:41

In reply to Re: Fluanxol (flupenthixol) for Bipolar ???, posted by X-ray on April 5, 2011, at 8:38:30

> > > Hello again!
> > > Flupenthixol is a classical/typical neuroleptic which is marketed (in England) as an AD at low doses (Fluanxol) and as an AP at high doses (Depixol). Occasionally, Fluanxol has been reported to induce mania/hypomania so that's something you need to watch out for!
> > > It sounds like it was very effective for your depression. If you decide to go back on the Fluanxol it's important to make sure that you're taking the minimum necessary dose, this is because it can cause tardive dyskinesia. The risk of TD is small if you are only taking a very low dose. The risk increases with length of treatment. Some people can benefit from doses as low as 0.5mg/day! Overall, the small risk of TD from low dose Fluanxol may be less important than the risk of obesity on Zyprexa (which also occasionally causes TD). This is something that you and your pdoc will need to discuss.
> >
> > What is the likelihood of getting TD from long term (several years) use of low dose (0.5 mg or less per day) Fluanxol?
>
> Hi,
>
> I switched from buspirone to flupenthixol two years ago.
>
> I take 0,5 mg in the morning and 0,5 mg in the afternoon, which is a low dose.
>
> So 0,5 mg of flupenthixol is a very low dose.
>
> I don't have expert knowledge, but I'm pretty sure that the risk of getting TD on 0,5 mg of flupenthixol is minimal.
>
> Best regards,
> X-ray

Thank you very much.


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