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Re: How is testosterone connected to depression? » PeterJ

Posted by maya3 on January 19, 2011, at 7:40:49

In reply to Re: How is testosterone connected to depression?, posted by PeterJ on January 18, 2011, at 16:28:47

Thanks, Peter.


> > Does that mean that high testosterone raises dopamine levels?
>
> Not in all brain areas, but it does in the prefrontal cortex (at least for male rats):
>
> http://cercor.oxfordjournals.org/content/21/1/222.long
>
> I have been on testosterone treatment for 17 years and an activating effect is subjectively clear and related to my serum T level. This effect is increased by inhibitors of estradiol production such as anastrazole, which I recently started.
>
> I could certainly see how too much T could exacerbate psychosis or mania and too little could worsen depression or anergia.
>
> Peter J (frequent lurker, rare poster)


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