Posted by Ron Hill on October 27, 2010, at 22:59:03
In reply to Re: Ultra Rapid Cycling Stopped Using Valdoxan » Ron Hill, posted by alchemy on October 23, 2010, at 13:42:26
> OMG, that gives me so much hope.
Your Mileage May Vary, but it stopped my ultra rapid cycling.
> Did the Valdoxan help with your depression as well?
Yes, by and large, Valadoxan stopped my depression. But, Valdoxan caused some noticeable amotivation and anergy during the day. This is odd since it releases DA and NE in the prefrontal cortex due to the antagonism of 5-HT2c. So, I added 2.5 mg of dexedrine spanules to take away the amotivation and anergy. The addition of the dex worked.
Since I take Nardil, I have to keep my p-stim dosage low for safety sake. Further, higher dosages of a p-stim might make me start rapid cycling. Also, p-stims eventually make me very irritable (GRRRRRRRRR!) over time even at dosages as low as 5 mg/day.
It should be noted that if I do not take my vitamins, I get depressed. If I skip one day, I'm okay; but anymore than that, and I get depressed.
> At least it sounds like I could take the dexadrine with it. I also chart my moods in excel, and the ultra ultra rapid cycling has become worse with the dex.
> But I have always had variability over an avg. of 3-5 days. Some are worse than others with no pattern at all (not even related to my menstrual cycle).
> It sounds promising that it works on circadian rhyths. I have been doing even more detailed research & know what M1 & M2 are!
> Ya, bipolar II is what fits me best- without the "ups". But I'm not really the atypical type as far as wanting to just stay in bed. I go through the tired cycling, but I usually kinda freak out about getting out of the house even if I don't feel like doing anything. Before this med combination I had mixed agitated depression. I am very sensitive to others, depression started in my early teens. One think that SSRIs have seemed to help in the past is lessening my sweet cravings (I almost had an eating disorder), and helped with the weight. But the dexadrine would take away those problems. I have always felt like I needed an SSRI, but they definintely may have contributed to the changes over a few days that have been going on forever.
If I were you, which I'm not, I'd dump the SSRI immediately and add a good moodstabilizer. I really like Trileptal (oxcarbazapine). Further, Valdoxan is worth a trial.
> Wow, I wish I could afford all of those supplements. I was actually at the store yesterday contemplating getting phosphatidylserene, but it was $20. I'm pretty regular about taking b-vitamins, magnesium, zinc, calcium w/ vit D, and fish oil.
You are taking some good vitamins. Please do this: Add 600-800 mcg of chromium picolinate and 2500-5000 mcg of sublingual methylcobalamin. Both are very affordable and can really help. Methylcobalamin is the endogenous form of B12. Further, it is VERY IMPORTANT to take B12 sublingually because if it is merely swallowed, only 1% is absorbed. However, when B12 is taken sublingually, 99% is absorbed.
Phosphatidyl Serine is great for the brain, but like you say, it's spendie.
> I tried Tegretal forever ago & thought I didn't like it, but that is the only thing I would give another try as an adjunct.
Forget about Tegretol; Trileptal is a much cleaner medication.
> I also have been often having a point where I get brain fatigue, where I can't handle thinking or doing anything anymore. That is especially not good on the job. Sometimes only an hour.
> I have been unemployed for a couple of months and have made a reasonable amount of money in the past. I do often worry that I am just not mentally stable & functional enough to handle work. But I usually miserably make myself.