Posted by SLS on October 20, 2010, at 14:54:02
In reply to Agomelatine » SLS, posted by sigismund on October 20, 2010, at 14:14:32
> >I have been losing sleep because of the sleep disruptions agomelatine is known to produce early in treatment.
> My two bob's worth is that the melatonin agonism is helpful to sleep and the 5ht2c antagonism can be disruptive of it (through the well known dopaminergic effect).
> The first time I took 25mg and slept for an hour or two and then was awake for the night.
> When I took 12.5mg thereafter my sleep was brilliant (for a while).
How would you describe the quality of your therapeutic response to agomelatine? Are you still taking it? Is 12.5mg as effective for you as 25mg?
The measure of achievement lies not in how high the mountain,
but in how hard the climb.
The measure of success lies only in how high one feels he must
climb to get there.