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Re: Zofran used off-label for social anxiety?

Posted by jerryTRD on October 18, 2010, at 18:52:38

In reply to Zofran used off-label for social anxiety?, posted by jerryTRD on October 18, 2010, at 17:25:06

> I've read online and in my Drug books that Zofran (Ondansetron) is/can be used for social anxiety disorder. I suppose this is because of it's effects on 5-HT3 receptors? But BuSpar does the same thing - why isn't it as helpful? Or am I wrong?
>
> Jerry

Ondansetron in social phobia
by M.S. Grunes, J.A. Yaryura-Tobias, F.A. Neziroglu
Biological Psychiatry (Vol. 39, Issue 7, Page 624)

Unlabeled Uses

Treatment of nausea and vomiting associated with acetaminophen poisoning or prostacyclin therapy; treatment of acute levodopa-induced psychosis (visual hallucinations); reduction in bulimic episodes due to bulimia nervosa; treatment of spinal or epidural morphine-induced pruritus; management of social anxiety disorder.

Read more: http://www.drugs.com/ppa/ondansetron-hydrochloride.html#ixzz12l2DOFj5


Major Depressive Disorder, treatment-resistant w/GAD. Meds: Lexapro 10mg, Adderall IR 20mg 3x daily, Klonopin 1mg 5x daily, Seroquel 300mg, Ambien 10mg, Synthroid 125mcg, Androgel

 

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URL: http://www.dr-bob.org/babble/20101009/msgs/966181.html