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Re: What will a pill do? - What will a pill not do?

Posted by bleauberry on September 24, 2010, at 17:14:08

In reply to What will a pill do? - What will a pill not do?, posted by SLS on September 23, 2010, at 22:49:08

> I'm moving this topic to its own thread.
>
> What will a pill do?
> What will a pill not do?
>
>
> - Scott

As evidenced by the sporadic occasional success stories here, pills can work miracles. Viewing the overwhelming numbers of less-than-success stories and digging deep into clinical studies, we see that the pills actually don't do great things as often as we would like. I think many clinicians must wonder why they can't get the same results as clinical studies.

I believe the mechanics of the pills are far beyond our knowledge. What we know they do is only one mechanism. Zyprexa research for example showed that it turned on or up 30 different genes, while at the same time turning off or turning down 30 others. Some of those turned up have to do with weight gain. Some have to do with mood. Some have to do with blood sugar.

Pills can do a lot of stuff besides increase neurotransmitters at the synapse. Which of those things, most of which we don't know about, is really responsible for the occasional success stories?

What a pill cannot do. Not a single psychiatric medication can clean corrupted or contaminated neurotransmitters. They cannot increase neurotransmitter production if there is a roadblock in mehtylation and other circuits. Indeed we may be trying to increase neurotransmitters at they synapse but there aren't enough neurotransmitters being produced to allow the drug to do that.

It is my belief that many more people than most of us would suspect have an immune system problem and an underlying unsuspected undiagnosable pathogenic load. Whether that was caused by a chronic infection, the stress of ongoing depression, or some other environmental impact, the immune system is tied closely to brain, hormone, and receptor functions throughout the body. Psychiatric drugs do not address the immune system angle.

Many doctors scoff at the idea of systemic candida. Yet people's brain fog, severe depression, and chronic fatigue vanish when they embark on an antifungal war.

The same can be said of things such as Lyme, MS, Fibromyalgia, and Chronic Fatigue. Almost all of these patients have depression that is either unaffected by psych meds, modestly improved, worsened, or confounded with sensitive complications. I remember one lady's story of how Parnate complete wiped out her CFS and FM symptoms. But that isolated success story is among about 100 others not so successful.

The pills will not remove heavy metals such as lead or mercury. I suspect if all of us were to take a 1200mg dose of DMSA and collect urine for the next 6 hours, we would see much higher levels of both of those metals than anyone would have thought. The metals disrupt everything....literally, everything...blocking receptors, killing receptors, contaminating stuff, enabling otherwise tame pathogens to flourish, clogging thyroid and can't be seen in thyroid testing, clogging adrenals, allowing large undigested molecules to leak through the intestinal lining straight into the blood stream. Just for starters. They also interfere with neurotransmitter production, disrupt methylation pathways and dozens of others.

From my own personal experience and research I have no doubt that contaminated neurotransmitters....not deficient neurotransmitters...cause serious depression. Toxins are what contaminate them. Toxins come from a leaky gut or from an unsuspected and likely undiagnosable infection...bacterial, viral, or fungal, likely a combination. I say undiagnosable because tests for many do not exist, and those that do are woefully flawed in accuracy.

What do the pathogens do to mess up our serotonin and dopamine? Well, 3 things. Poop. Pee. And chemical trails developed over thousands of years of evolution that trick the immune system into backing off. Basically, if you have a load of poop and pee flowing through your blood into your brain and receptors throughout your body, you are going to feel depressed and feel like crap.

Our pills won't touch any of the things mentioned thus far.

Most people are like me....
1. I never heard of that, so it can't be true.
2. My doctor doesn't know anything about it, so it can't be true.
3. My test came back negative so I don't have these problems.
4. It couldn't possibly be that bad.
5. Certainly my immune system would take care of it, right?
6. It only happens to other people, not me.
7. It is so rare as to not even consider it.
8. It's all just theory or anecdotal, no scientific validation....as if anything in depression is solidly validated....nothing is...everything we do to treat depression is EXPERIMENTAL...herbs, psych meds, vitamins, exercise, light, antibacterial, antifungal, antiviral, gut healing, and such...psych meds are more widely accepted, but by no means more effective or solidly proven in any shape, manner, or form.

Well, that was me 5 years ago. Today I know for a fact it is all as true as the sky is blue. The most significant depression relief I have ever encountered included the following:

1. DMSA. Picks up lead and mercury molecules and takes them out of the body. Also mops up some of the toxins of pathogenic invaders.
2. Doxycyline. Once the bugs, whatever they are, start dying, things get a lot worse (more toxins from all the corpses that can't be flushed out fast enough). But during the early days, hello remission! That's when the bugs were initially paralyzed...their pooping and peeing is stopped...but they aren't dying yet.
3. Diflucan. Same as above, except with fungi such as Candida or other versions picked up from dirt, attics, basements or traces of mice feces.

Several anti-microbial herbs did the same thing.

My problem is that the Herxing gets so bad I can't get to the other side. But for sure, during that short window in the early going, I have proved a dozen times that "other" meds besides our usual psych pills were the ones that delivered true remission...not a fake or manufactured remission, but a return to your former self pre-depression days.

You ask a very complicated question Scott. I don't think anyone on this planet knows the answers. All I am saying is that there are a handful of major depression causers all around us that are completely ignored, and none of them respond to psych meds very well. They aren't doing the right stuff, which is basically removing toxic load from body.

Example. If someone is on 120mg parnate, we can be fairly well guaranteed they are flooded with plenty of serotonin, NE, and DA. But what if there is lead, mercury, pee, or poop, mixed in with it all? Now we are looking at someone on 120mg parnate who feels like crap despite the plentiful supply of neurotransmitters.

While I've covered some of the bases that are personally close to my own situation, we haven't even mentioned things like the sheaths around nerve endings, receptor sensitivity, receptor density, inadequate blood flow in the brain, or inflammation of the brain. All these things bring us full circle right back to where I started...it's something related to the immune system, not a direct fault of the brain itself.

My overall message here is that we live in a toxic era. All that lead from leaded gasoline 40 years ago? It's still out there, everywhere. Mercury everywhere. Lyme diagnosed at only 1/10th its actual rate. Crippling fungi found in simple basement dust. On and on. Throw in the mix what we earthly humans consider an acceptable diet, and forget it, we are sitting ducks.

The pills can work miracles, but in my opinion only address a small piece of the pie. Most people think the rest of the pie is just too hard to deal with, so stay stuck in the small piece, not realizing the rest of it is actually pretty simple and straight forward to detective work with. But it's easier to just keep the appointment with the pdoc next week and try yet another pill that does something to serotonin and dopamine.

When a bunch of psych meds don't do the trick, it is only pure unadulterated logic that says...."you're barking up the wrong tree if you're only looking at brain chemicals".

IMO


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poster:bleauberry thread:963581
URL: http://www.dr-bob.org/babble/20100917/msgs/963627.html