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Re: so is low dose zoloft safe with dosulepin? » rovers95

Posted by SLS on September 5, 2010, at 8:31:41

In reply to so is low dose zoloft safe with dosulepin? (nm), posted by rovers95 on September 5, 2010, at 7:51:47

I believe so. Zoloft is not as potent a CYP450 2D6 inhibitor as are Prozac and Paxil. Still, you may need to adjust the dosulepin downward somewhat as 2D6 is the primary route of metabolism for this drug. At 50mg of sertraline, you probably won't need to make any adjustment in dosulepin at all.


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