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Re: Tricyclic Lovers: Desipramine or Pamelor

Posted by Brainbeard on May 31, 2010, at 6:41:57

In reply to Re: Tricyclic Lovers: Desipramine or Pamelor, posted by bearfan on May 27, 2010, at 14:15:34

> I thought desimpramine had nearly the same effect as tofranil . I am wrong here ?

Yep. Desipramine is a metabolite of Tofranil (imipramine). Imipramine is not only an NRI but also a strong SRI. Desipramine lacks affinity for serotonin transporters.


Current meds: 10mg melitracene + 0.5mg flupentixol; sertraline 100mg; amitriptyline 25mg; gabapentin (Neurontin) 300mg; melatonin 0.3mg. PRN: diazepam (Valium) 2.5-5mg.


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