Posted by vaisforlovers on May 20, 2010, at 21:42:37
In reply to Re: NARDIL Dosage Increase? » jedi, posted by bulldog2 on May 11, 2010, at 9:49:21
You are right about there being much more involved beside neurotransmitters in the efficacy of meds. I have been reading about the Cytochrome P450 enzyme system and how our genes can be predictors of how a med will work. This is fascinating but unfortunately, a whole bunch of research has to be done and is of course cost prohibitive. I just read where patients can be deficient in an enzyme that metabolizes a drug and said drug will not work as expected. And that is probably the reason some drugs have to be given at much higher doses than normal. But since this technology is a long way off to be used in every day medicine and the docs are not up to date in this stuff, it is the patient that suffers. How sad. I have a hard time getting my doc to increase any med even tho' I tell him that the drug just isn't working. If it isn't in the PDR, they won't prescribe it.
I am on 15mg 4 times a day of Nardil. My problem is that I forget to take all of the doses and I can feel the effect in my degree of depression. I think I should be on an increased dose. In fact now that I have read this thread, I am going to ask the doc to increase it. I have also taken abilify with good results.
I am also on ambien and the only problem I have from that is occasional amnesia if I don't go right to bed.
poster:vaisforlovers
thread:946832
URL: http://www.dr-bob.org/babble/20100514/msgs/948126.html