Posted by med-amorphosis on May 17, 2010, at 18:05:23
In reply to Re: Imipramine really that good?, posted by ed_uk2010 on May 17, 2010, at 15:38:39
> >So why has my pdoc included it in the list of TCAs he 'will' consider adding to my MAOI, as well as amitriptyline?
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> I must say that I am very surprised.
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> >Anyway, imipramine is greatly more potent as an NRI than SRI, esp as its broken down to desipramine anyway. No?
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> Imipramine itself acts as a moderate SRI and a NRI. Desipramine is an NRI. I would be very concerned about combining imipramine with any of the MAOIs. Fatalaties have been reported.
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> eg. Imipramine added to the MAOI tranylcypromine (Parnate)...
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> http://www.ncbi.nlm.nih.gov/pubmed/12927331
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>But im taking Marplan not Parnate. Very different drug. Thats the problem with MAOIs- they are now looked upon as one group of similar drugs, like SSRIs. BUT, MAOIs are totally unique to each other. None are the same, or even similar. Trust me. I've found I can get away with allmost anything with Marplan, unlike Nardil. Pizza? YES! Cheese strait from the block? YES! Could I do this on Nardil? NO!
poster:med-amorphosis
thread:947687
URL: http://www.dr-bob.org/babble/20100514/msgs/947728.html