Posted by vic80 on May 15, 2010, at 13:33:55
Currently tapering down Lexapro 10mg > 7.5mg(today) 2 days > 5mg 2 days > 2.5 mg 2 days > stop (6th day from today) (have already been tapering down lex from 20mg a month ago > 15 mg > 12.5 mg 10 days ago > 10 mg a week ago)
tapering down Lorazepam - 0.5 - 0.5 - 1.0mg -> 0.5 - 0 - 0.5mg for the next 7 days
Started on Milnacipran 25mg Today morning:
Felt nausea - tingling in the legs and an increased heart rate. Plus some strange sort of fatigue and aches in the lower body.Past few days I have been going crazy - songs and words stuck in the head - constant mind chatter, unreality and a general feeling of going crazy - this could well be the lexapro withdrawal.
I didnt feel any difference emotionally through the day after taking MIL 25mg in the morning, I noticed an elevation in mood in the evening - which was not abnormal or even remotely hypomanic. (could well be lex taper)
been having shivers in my scalp/cranium past few days esp. on the right side. Today I noticed the shivers/zings in other joints of the body too - mainly knees and hips....never the less I was all over the place as usual - feeling completely spaced out - this is normal on lex taper I guess.
I have tried VenlafaxineXR in the past but a single dose taken in the night made me feel like my brain was totally frozen next day. COuldnt think or feel - was just sitting and staring at the walls.
What I felt 12 hours after taking my Milnacipran is just similar a monotonous mood - not happy not sad - not bothered - not scared not angry - nothing. PLus its difficult to think.
have constant aches/tingling through the body at different points - back aches and my heart rate is 96.Could it be that i react badly to NE re-uptake drugs..
I have heard a lot of praise for Milnacipran - but its mode of action is through the inhibition of NE and serotonin re-uptake which makes it quite similar to Venlafaxine (except that MIL has much higher NE reuptake Inhibition).
My main concern is persistent apathy and anhedonia which started during lexapro, my doc thinks Milnacipran would help address this and make me feel more motivated and emotional, would also help with the underlying anxiety etc.
There isnt much info on Milnacipran on the internet, except that its reportedly as good as TCAs in crushing depression minus the dirty effects.
Any inputs on Milnacipran's efficacy on OCD (mainly obsessive) and Depresonalization/Dissociation?
poster:vic80
thread:947505
URL: http://www.dr-bob.org/babble/20100514/msgs/947505.html