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Re: Alternating SSRIs monthly? » Brainbeard

Posted by orbital on March 20, 2010, at 11:26:05

In reply to Re: Alternating SSRIs monthly?, posted by Brainbeard on March 20, 2010, at 10:29:16

BBeard, I've been adding 10mg Prozac to my 20 mg Lexapro a couple of times a week - my pdoc frowns at this. When I do it, I notice a surge in energy etc the *next* day, but it's very limited. Lower doses of either med do nothing for me.

I'm warming to the alternating thing. For instance, I'm starting a new job soon, so I'd like to be calm and collected during the first few weeks - hence, Lexapro. I know I'm bound to burn out further on, at which point I could switch back to Prozac.

Of course I could try a different med altogether, but really, I'm tired of failed trials; these two do work for me, in very different ways (I consider them to be polar opposites in the way they affect me). I also seem to respond extremely quickly to both. I typically feel the Prozac stimulation like 2 days after starting it, and Lexapro is like a sleeping pill for me - instant effect. Switching them at regular intervals could also prevent poop out.

Thanks for your response :) I appreciate your insights.

> Hooray! to an interesting suggestion.
>
> I have pondered about taking all SSRI's simultaneously in micro-doses, but this is also an interesting idea. 'Which month is it? -It's Prozac month, currently, Zoloft month in three days from now.'
>
> Prozac of course has a very long half-life, and it will stay in your blood for at least a month after having taken it for four weeks or more. Prozac also inhibits Lexapro's metabolism, boosting its levels in the blood.
>
> Perhaps adding low dose Prozac to regular dose Lexapro might help (I won't get into the technical details here, but theoretically it could make a difference). Or adding low dose Lexapro to high dose Prozac? The possibilities are endless.
>
> I have taken low dose Prozac (5mg) a couple of times while on 5mg Lexapro, but couldn't notice the usual effect I get (stimulation, motivation) when taking low dose Prozac on its own (or together with Valium, a combination that can work truly wonderful for me).
>
> I suggest any Lexapro<-*+/-*->Prozac experiences will be reported in this thread.


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URL: http://www.dr-bob.org/babble/20100318/msgs/940178.html