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Re: How bad is tricyclic weight gain + anorgasmia???

Posted by Brainbeard on March 16, 2010, at 16:28:44

In reply to How bad is tricyclic weight gain + anorgasmia???, posted by Walfredo on March 16, 2010, at 12:34:31

> I know all this stuff is different for different people but I'm just curious what the consensus is on:
> A) weight gain
> B) sexual side effects - libido, anorgasmia, erectile dysfunction

Clomipramine is worst for sexual side-effects since it's the strongest SRI; imipramine's already better, amitriptyline even less offensive, nortriptyline no problem at all, desipramine ditto.

The primary amine TCA's, clomipramine, amitriptyline, imipramine, are the worst offenders for weight gain, with amitriptyline probably leading the pack, at least at high doses, and clomipramine probably second. Nortriptyline also makes some people gain weight fast, but it can be less of a problem. Desipramine would be most weight neutral.




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