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Re: SSRI-induced Apathy - short OR long term use?

Posted by sukarno on March 16, 2010, at 3:46:18

In reply to Re: SSRI-induced Apathy - short OR long term use?, posted by manic666 on March 13, 2010, at 6:27:29

SSRIs cause apathy in the long term in many folks because, by boosting serotonin through reuptake inhibition, the number of dopamine transporters increases by up to 50% about 4 weeks into treatment.

This lowers the amount of dopamine in the synapse.

Basically, SSRIs can have a neuroleptic-like effect in the long term.

This is what causes weight gain, apathy, loss of libido and even movement disorders.


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poster:sukarno thread:938982
URL: http://www.dr-bob.org/babble/20100305/msgs/939689.html