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Re: Stimulants helping more over time?

Posted by linkadge on March 14, 2010, at 11:22:29

In reply to Re: Stimulants helping more over time?, posted by West on March 14, 2010, at 10:38:57

The effects of 5-ht1a agonism and norepinephrine reuptake are likely convergent / synergistic.

5-ht1a agonists have procognative effects by releasing prefrontal dopamine. The norepinephrine transporter inhibition will prolong the activity of that dopamine (at least in the prefrontal cortex).

Linkadge


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URL: http://www.dr-bob.org/babble/20100305/msgs/939509.html