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Re: Everything You Ever Wanted To Know About Savella

Posted by SLS on December 28, 2009, at 18:43:16

In reply to Re: Everything You Ever Wanted To Know About Savella, posted by bleauberry on December 28, 2009, at 18:21:17

> SLS has a suggestion for an anticholinergic. The thing is though, savella doesn't really have any appreciable cholinergic effect. That said, I learned a long time ago to forget the theory crap...it doesn't work...an anticholinergic like SLS mentioned could indeed work very well. I would love to see someone try it and see. Maybe it will be me.


I'm not sure how Flomax would help. Urinary retension and delayed micturition need not be the result of using a drug with anticholinergic properties. It can occur as the result of excess sympathetic activation. Either way, a parasympathetic pro-cholinergic like bethanechol may still make sense to try first. Flomax works on the alpha-1a/b receptors in the prostate. I don't think it affects smooth muscle tone in the bladder like bethanechol does. If Flomax works, that would be great. I imagine it would be pretty expensive, though.


- Scott

 

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URL: http://www.dr-bob.org/babble/20091227/msgs/931319.html