Posted by bleauberry on December 9, 2009, at 17:03:56
In reply to Nortrioptyline question, posted by morganator on December 9, 2009, at 4:30:26
I don't remember what other meds you are on?
If one is an SSRI, you may discover as you are weaning down and introducing nortriptyline at the same time that the mixture is very good. It's quite possible. Whatever other meds you have, I doubt they will play a role. SSRI+nortrip just happens to be a pretty reliable bet most of the time, better than either alone.
As for sleep, well, if that is a serious issue, I am not sure if nortrip will do that or not. It could, but it is not famous for that. Norepinephrine meds like Milnacipran or Nortriptyline happen to improve my sleep, presumably by activating the feedback loops that slow down overactive adrenaline circuits.
For serious sleep issues, my two favorites are:
2. Ultra low dose Remeron (1mg - 7.5mg). These very low doses, almost crumbs, are so much more sedating than therapeutic doses. From what I can "feel" and "hear" (as in tinnitus), the norepinephrine stimulation of remeron begins around the 7.5mg dose...anything less is almost purely antihistamine and serotonin receptor blockade...both powerful pro-sleep.
3. Occasional use of Klonopin works good too...but not to be used on a regular daily basis.
I've never tried it, but amitriptyline is supposed be excellent for sleep.
I do not favor the use of antipsychotics in nonpsychotic patients for purposes of sleep. Messing with the dopamine system is risky and should be reserved for cases where there is much more at stake than just a sleep issue. My opinion.