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Re: Umm. Let's Not Ignore the Science

Posted by mtdewcmu on December 1, 2009, at 11:15:12

In reply to Umm. Let's Not Ignore the Science » SLS, posted by Ron Hill on December 1, 2009, at 2:49:39

> Please scan the links, my very good friend:
>
> http://www.cma.ca/multimedia/staticContent/HTML/N0/l2/jpn/vol-31/issue-2/pdf/pg84.pdf
>

That article postulates a mechanism; it doesn't prove that exercise works. You should have posted these studies instead (quoted from the paper):

"Most germane to the present article are the recent studies that have assessed the effects of exercise on patients with MDD. Three articles are of particular interest. First, Dimeo et al99 assessed the efficacy of exercise in the treatment of moderate-to-severe MDD. In this study, exercise significantly alleviated the condition. In the second, Mather et al100 assessed the effects of exercise classes as an adjunct to antidepressant medication. The patients who participated in the exercise classes displayed greater improvement than did the control patients, who attended health education talks. Third, Dunn et al101 assessed the effect of the dose of exercise on 80 adults with MDD. There were 3 conditions: moderate aerobic exercise, low-intensity aerobic exercise and flexibility exercise. The moderate aerobic exercise group improved significantly more than the other 2 groups."

> http://www.ulbruxelles.be/facs/ism/docs/behaviorBDNF.pdf
>

Same problem.

> http://www.physci.ucla.edu/research/GomezPinilla/publications/ReviewHormesis.pdf (click down to access all 14 pages)
>

This article is a literature review, not a study. It doesn't contain proof of anything.

> http://www.springerlink.com/content/g441495247401673/fulltext.pdf?page=1
>

I can only see one page of the preceding article.

> http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0F-4SSG51F-2&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1116628132&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=f43c768f9daa8b8dd758047714811b88
>

That study deals with DHA, not exercise directly. Moreover, the experiment was done on rats, which will exercise spontaneously unless they are kept in confinement. So, studies on rats tell us more about the negative effects of confinement than they do the positive effects of exercise.

It's too tedious to go through all of these articles. Reply with 2-3 good ones if you can.

Neal


> http://content.karger.com/produktedb/produkte.asp?typ=pdf&file=000223730
>
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614307/
>
> http://books.google.com/books?hl=en&lr=&id=3ykTAQ7QIegC&oi=fnd&pg=PA33&dq=BDNF+exercise+depression&ots=Awf7zrzXog&sig=w5r8n2IZ25Ue2o7EU8phqsszrkc#v=onepage&q=BDNF%20exercise%20depression&f=false
>
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597158/
>
> http://www.nature.com/npp/journal/v33/n11/full/1301671a.html
>
> http://bmbreports.org/jbmb/jbmb_files/%5B42-5%5D0905250942_(239-244)BMB222.pdf
>
> http://www.psychosomaticmedicine.org/cgi/content/full/62/5/633
>
> http://svaynman.com/images/exerciseBDNFcognition.pdf
>
> http://jn.physiology.org/cgi/content/full/88/5/2187
>
> -- Ron
>
> dx: Bipolar II with ultra rapid cycling and mild OCPD
>
> 600 mg/day Trileptal
> 200 mg/day Lamictal
> 500 mg/day Keppra
> 90 mg/day Nardil
> 1.9 mg/day Deplin (taken with methyl B-12 and P-5-P)
> Dark therapy via LowBlueLight glasses
>
> ------------------------------------------
>
> > I think that this is another case of needing to acknowledge the interindividual differences that exist in the presentations of what we are all calling "depression". I never tried performing vigorous aerobic exercise every day for 3-4 weeks. I have lifted tons of weight, though. My exercise schedule comprised 4 times a week with alternating muscle groups. I did this for years without gleaning any benefit for my depression. There was a time when I did take brisk walks of 5 miles every day. Again, no help.
> >
> > I think one needs to respect the potential for depression to render one nearly motionless with paralyzing psychomotor retardation and suffocating anergia. To intimate that a person with such a presentation can exercise if they were only to try hard enough can insinuate that they perhaps are somehow inferior and simply do not want to do what might be necessary to get well. Of course performing exercise is generally a good thing. But that doesn't mean that everyone is capable of it. Fortunately, there are other ways of treating depression. Exercise is not a necessary component of most treatment regimes. Actually, there are a few doctors who believe that intense anaerobic resistance exercise like weight-lifting can make someone feel worse instead of better - something about depleting brain amines. I don't know if I agree with this, though.
> >
> >
> > - Scott
>
>


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poster:mtdewcmu thread:926857
URL: http://www.dr-bob.org/babble/20091127/msgs/927688.html