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Re: Stimulants for TRD tensor

Posted by floatingbridge on November 13, 2009, at 17:57:11

In reply to Stimulants for TRD, posted by tensor on November 13, 2009, at 4:31:35

> Hi,
> what are your experiences with using stimulants as amphetamine for treatment-resistant depression? I used to take modafinil for a pretty long period of time but it simply does not work anymore. So I'm now looking at other options.
> I was thinking that I could take it monday-thursday and have a drug holiday friday-sunday as I did with modafinil to not develop tolerance, this way I would at least get things done four days a week as opposed to zero now. What do you think?
> Thanks.

Hi Tensor,

Well, I've been taking Dexedrine for 8 months now, along w/ pristiq and various benzos (anxiety was a problem before the dex came on board. I've built up a tolerance, but not to the mood elevation--I mean, it is not the euphoria I first experienced, but it stills brightens me in a way nothing else has. I deal w/ the crash in various ways, and it's taken months to figure out a way to minimize the crash (which can be very ugly and painful). I am going to try the brand dexedrine spansules. I found out my insurance will cover them for not much extra. Generic IR and the Barr generic spansules do not last nearly as long as they should. The Barr spansules wear off after 4-5 hours! (The pamphlet says 10-12!) (I did not respond well to provigil.)

I've never taken drug holidays, so I cannot speak to that. I keep my daily dex consumption low and do not increase unless in an emergency.

Hope this was of some help. Do you take any other meds?




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