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Re: d-amphetamine + caffeine use in OCD - study

Posted by bulldog2 on November 4, 2009, at 14:40:15

In reply to Re: d-amphetamine + caffeine use in OCD - study » bulldog2, posted by Phidippus on November 4, 2009, at 14:35:45

>
> > Are any tricyclic ads capable of nmda antagonism?
>
> All ADs modulate glutamate.
>
> > How much amantadine is needed for nmda antagonism?
>
> amantadine 100-400 mg/day
>
> > I wonder if amantadine is easier to tolerate than memantine which really wired me up?
>
> Memantine is a D2 agonist which probably accounts for the wiriness. BUT, Amantadine also does this. Memantine just has a more complicated mechanism of action.
>
> P
>
>
>
>
>

Thanks...Is there any ad that is the best as an antagonist of nmda..For some reason I recall tricyclics being mentioned but cannot find the research.

 

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poster:bulldog2 thread:924126
URL: http://www.dr-bob.org/babble/20091029/msgs/924450.html