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What permanently down-regulates acetylcholine

Posted by rovers95 on October 19, 2009, at 14:47:31

In reply to Re: best anticholinergic antidepressants?, posted by linkadge on October 12, 2009, at 14:31:39

> cogentin has no real studied effect in depression. It has anticholinergic effects. I believe it is also a weak dopamine reuptake inhibitor. It has abuse potential and may have antidepressant properties.
>
> Amitriptyline is a potent anticholingeric and antidepressant. It would probably be easier to obtain.
>
> Linkadge

Thanks again linkadge, from a few posts of yours i've seen it looks like perhaps your interested in long term anti-cholinergic mechanisms like myself, do you (or anyone else on the board) know of any med or even a herb, works in this manner?

Most of the stuff i've had a look at seems to cause a supersensitivity in acetycholine receptors following down-regulation and i believe both cigarettes (nicotine?) and scopolamine has had this effect on me?! like one of your posts i read im actually thinking if i went back to smoking long term i may be much better!

cheers

rover

 

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