Posted by sowhysosad on September 12, 2009, at 16:06:51
In reply to Re: Increasing SSRI/SNRI above the 'regular' doses » sowhysosad, posted by SLS on September 12, 2009, at 6:47:59
> You are one heck of a smart guy. I believe you are right about the occurrence (allowance) of a severe discontinuation syndrome producing subsequent over-sensitivities to medications and an increase in the severity of withdrawal symptoms.
Thanks Scott, but I believe it was you that first put the idea in my head so I can't claim any credit!
I rode out the worst start-up effects on fluoxetine (albeit at only 10mg) and I believe my 5HT receptors may have desensitized again.
My theory was that hitting the receptors hard with elevated serotonin levels in the synapse would force them back into compliance!
However, I still have the aforementioned spells of tachycardia/agitation/dysmorphia which I believe might be mediated through fluoxetine's noradrenergic mechanism rather than its serotonergic one.
I might ask to switch to a cleaner SSRI like escitalopram to see if it improves.
poster:sowhysosad
thread:916056
URL: http://www.dr-bob.org/babble/20090912/msgs/916724.html