Posted by doxogenic boy on September 4, 2009, at 14:29:52
In reply to Re: My medication history 1994 to 2009 » doxogenic boy, posted by SLS on September 4, 2009, at 8:34:30
> I wrote a long post in response to yours, but lost it.
Thanks for your work with it.
> To summarise:
> Keep the tianeptine and escitalopram since they are working for you.
> 1. I wouldn't bother with Wellbutrin again at this juncture. It will probably treat you the same as it has in the past.
> 2. You could try adding Remeron right now and use dosages between 45-75mg. Most doctors allow their patients to languish at 30mg. This is silly.
Can Remeron work with my current combination when the somewhat similar mianserin (Tolvon) up to 180 mg in combination with paroxetine 60 mg (spring 1996) didn't work?
I tried Remeron with sertraline November 2004, and I woke up early in the morning and felt so hungry that I had to stand up eating, if I wanted to sleep any longer. When I used mianserin, I gained many kilos, Remeron didn't I try so long.
> 3. It sounds like you might be a tricyclic responder. Switch to a TCA with a better track record for treating depression. You could taper the trimipramine gradually while titrating drugs like amitriptyline, doxepin, or nortriptyline. Nortriptyline does not increase anxiety in most people.
> 4. You could try adding low-dose lithium in the dosage range of 300-600mg. You will know within two weeks whether or not it will be of any value. For those people who are use it as an augmenter of antidepressants, it can work as soon as a few days.
How does it feel, if low-dose lithium works, as augmenter of antidepressants? Does it work against anxiety, anhedonia, worrying and does it make you feel calm and/or more motivated?
I tried lithium in 1994/95, about half a year, then I had a manic-depressive (bipolar) diagnosis (it was replaced by a recurrent depressive disorder diagnosis about ten years ago).
My blood levels was measured, so it was in the therapeutic window for bipolar patients.
I felt indifferent, and except of the first two months, I had a "stable" depression and it made me indifferent. I felt free and better when I discontinued it. But a low-dose lithium treatment may be better, even with my bad experiences?
> It is hard for me not to recommend lithium as an adjunct worth a quick trial because I am currently having success with it.
OK. I have heard that a lot of people here where I live have found quetiapine (Seroquel) helpful.
It has both hypnotic, anxiolytic, antidepressive and mood-stabilizing properties, and it has worked like that for me, to some extent. With all my medication trials, it seems that keeping meds that have some effect, is the best I currently can reach.
I have a partial response to my current mix, and even though that still is bad, it is heaven compared to the worst anxiety/depression period August 2004 to December 2006.
A problem I still have, is that I am very depressed the first half or 3/4 of the day and have many mood swings each day (not hypomanic, just depressed/anxious and less depressed/anxious)
Is it possible to get rid of that without becoming blunt?