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Re: bifeprunox et alia and psychotropics

Posted by yxibow on August 26, 2009, at 0:14:28

In reply to Re: bifeprunox dropped » iforgotmypassword, posted by SLS on August 25, 2009, at 13:02:45

Forgot to add though about the pace of psychotropics... for every person who tries an agent just out of the pharmacy, they are the first Phase IV patients.

That means complete in real life situations with people already on other medications not already in the studies.

Would I want to be the first to try something that my doctor hasn't heard much chatter about yet ? I'm not really sure considering I've been through rough side effects of things.

Yet, Saphris (asenapine) does peak my curiosity...

Will it be a more liable or less liable (side effect, potential long term effect risks) atypical since it is molecularly completely different from other agents.

Invega I could already put at the top of liability since its basically Risperdal, its nothing new.

And there have been more proven tardive cases with Risperdal (at least at substantial doses) than other medications since it grabs the strongest hold on D2 of atypicals.

As I see it now its sort of {Risperdal/Invega}-> Geodon->Abilify->Zyprexa->Seroquel->{Clozaril}.

But this of course doesn't apply to everyone, just how I would see it possibly apply to myself, being unusually sensitive to APs. I don't even want to think about what happened with Zyprexa..

And people with affective disorders tend to be more prone to EPS and other issues with APs than those with schizophrenia, in general.

-- tidings

 

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poster:yxibow thread:913996
URL: http://www.dr-bob.org/babble/20090818/msgs/914120.html