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Re: bifeprunox dropped

Posted by jrbecker76 on August 25, 2009, at 22:52:44

In reply to Re: bifeprunox dropped iforgotmypassword, posted by SLS on August 25, 2009, at 13:02:45

> Yeah. That does suck. It might have been a better Abilify-type drug as an adjunct medication for major depressive disorder and bipolar depression. Perhaps without the weight gain?
>
> Unfortunately, it seems that DA partial agonists like Abilify and bufeprunox don't make the best antipsychotics when used as monotherapy to treat schizoid disorders. They are real good as an adjunct for negative symptoms, though.
>
>
> - Scott

Speaking of Abilify, Otsuka is currently in trials testing a tweaked version of the Aripiprazole compound. It's most likely a metabolite or an enantiomer of the current molecule. Innovative, eh.


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URL: http://www.dr-bob.org/babble/20090818/msgs/914106.html