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Re: Augmenting Nardil with ? bulldog2

Posted by SLS on August 25, 2009, at 12:53:56

In reply to Re: Augmenting Nardil with ?, posted by bulldog2 on August 25, 2009, at 12:20:42

> Scott I believe in one of the studies you gave Maxime one doc mentioned his best successes with maoi+amitriptyline.

I saw that. I might be wrong in showing concern about that combination.

Interestingly, I developed serotonin syndrome from mixing Nardil with imipramine, but not Parnate with imipramine.

Imipramine is a more potent reuptake inhibitor than amitriptyline. I think there is a 2-3 fold difference in their Ki. Still, amitriptyline is strong enough to have created concern in my mind. If it is indeed safe, that would be great. More people can get well.


- Scott

 

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