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Re: Will 50mg Amitriptyline -) 50mg Nortriptyline?

Posted by bulldog2 on August 24, 2009, at 11:16:29

In reply to Will 50mg Amitriptyline -) 50mg Nortriptyline?, posted by linkadge on August 24, 2009, at 10:34:23

o> When amitriptyline converts to nortiptyline can one expect the same blood level of nortriptyline as with an equivalent dose of nortriptyline?
> I.e would 50mg of amitriptyline eventually produce the same blood level of nortriptyline as 50mg of nortriptyline?
> If so, wouldn't the theraptutic dose of amitriptyline be lower as you essentually have two AD's in the system?
> Linkadge

No. I read that 2 milligrams of amitriptyline equals 1 milligram of nortriptyline in terms of the therapeutic window. Maybe each milligram of amitriptyline only produces a minute amount of nortriptyline. Just speculating. Can only tell you what I read.




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