Posted by cactus on August 18, 2009, at 16:00:04
In reply to Re: Nortriptyline update, posted by SLS on August 18, 2009, at 13:49:06
I'm sorry I should have added that I had much worse side effects from SSRI/SNRI's compared to TCA's. Yes scott you are SO right about different reaction for different people. My worst problem with TCA's was over sedation, but with SSRI/SNRI's the side effect list was way more extensive. I just really hate being over sedated to the point of ataxia, which for me involves anything that hits histamine receptors hard.
> Gosh, it still amazes me how differently people can react to the same drug.
> > My pdoc has that lined up for me if Edronax(reboxetine) doesn't work out. Have you tried it?
> Reboxetine put me in a severe, anxious, and suicidal depression.
> > It's not dulling like a TCA
> I have been on and off TCAs since 1982. The only one I feel was dulling was amoxapine. Perhaps this was due to DA receptor antagonism. Right now, I am taking 150mg of nortriptyline. It might as well be a sugar pill with respect to side effects. Only high dosages of imipramine made me feel a bit stupid. This is probably an anticholinergic effect. I should add, though, that I did experience many of the classic TCA side effects when I first started these drugs. For me, long term treatment seems to have allowed these things to mitigate greatly.
> - Scott