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Re: How Does Remeron Work For You All? Phillipa

Posted by SLS on August 18, 2009, at 5:27:35

In reply to Re: How Does Remeron Work For You All? SLS, posted by Phillipa on August 17, 2009, at 21:31:08

> Another neutral med for me why is luvox the only ad that affects me at all as brain seems to need it. If it's in the middle of SSRI's what other SSRI's are similar in strength? Love Phillipa

Zoloft and Paxil seem to be the "strongest". I think Prozac is the "weakest". Celexa, Lexapro, and Luvox are somewhere in the "middle".

These represent the binding affinity (dissociation constant) of the drug to the receptor on the 5-HT transporter. They do not represent effectiveness. Prozac, being weaker than Luvox, is still, in my opinion, a more potent drug to treat depressive disorders. Luvox is, however, the most efficacious for treating OCD. In vitro binding affinities alone must therefore not be the whole story as to how these drugs work.


- Scott

 

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