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Re: seroquel adjunct

Posted by bleauberry on June 23, 2009, at 17:04:13

In reply to seroquel adjunct, posted by markwell on June 23, 2009, at 11:08:01

Just my two cents here. I could show you a bunch of studies, dig into them, show you hundreds of comments from other patients, and all that. The end result is this:

In my opinion Seroquel is a poor choice. Zyprexa would have been a much more solid choice. Again, I won't go into why, just know that I say with plenty of reasoning behind it. I don't just make stuff up out of personal bias.

Paxil is probably the most guilty of all the SSRIs at inducing mania in either bipolar or unipolar patients.

Zoloft is probably the most solid choice as I see it. Nortirptyline is a good choice. Both together even better. The problem is that with Seroquel as the stage, that really messes up the whole picture.

Since the Paxil induced the mania, the mania is behind you, then I see no reason why you should still be on Seroquel. A slow weaning should be considered. Even in case studies or clinical studies by the hundreds all over pubmed, as soon as the patient is stabilized from whatever the problem was, they then begin to wean them off the meds and see what happens.

If things fall apart, start Zyprexa instead of Seroquel. Or do a straight across swap to Zyprexa and add Prozac with it. That has a very powerful antidepressant action and very low manic induction.

I know some other people really like Seroquel. I'm not bashing it. I am saying that I can back up my opinion that if given a choice, Zyprexa has much better potential. I do not understand why doctors use Seroquel as much as they do, unless maybe it has something to do with the success of the pharm reps visiting their offices, or they are afraid of the Zyprexa weight gain/diabetes risks, which are pretty much nill when doses are kept low to medium and the patient accepts responsibility for the foods they buy.

I can't give you any ideas what to add to Seroquel because I don't think that road goes anywhere.


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