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Re: Valium defeats Prozac's antidepressant effects?

Posted by linkadge on June 19, 2009, at 17:05:47

In reply to Re: Valium defeats Prozac's antidepressant effects?, posted by West on June 19, 2009, at 16:45:11

Well, there have been studies in which mice responded to fluoxetine independant of neurogenesis. Also, some mice strains actually do not show neurogenesis in response to fluoxetine.

Valium could reduce the effect of fluoxetine for other reasons all together. Valium is a downer. In the absence of significant anxiety, it may just be a behavioral depressant.

Keep in mind though, that while fluoxetine does increase neurogenesis in non stressed animals, some studies show that it failes to protect animals agains the neurotoxic effects of stress. On the other hand, in the same study, tianeptine and a benzodiazapine did.

Linkadge


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poster:linkadge thread:902045
URL: http://www.dr-bob.org/babble/20090611/msgs/902098.html