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Re: Buspirone Dosage Philippa

Posted by X-ray on May 15, 2009, at 4:21:12

In reply to Re: Buspirone Dosage » X-ray, posted by Phillipa on May 14, 2009, at 20:03:19

> X-Ray if You've become tolerant of benzos so they make you tired instead of give energy like they used to would Buspirone work for anxiety? Was on it years ago in combo with benzos but then they only gave 5mg a day? Please reply. What is all this talk about possible psychosis that I've read about with buspirone? Thanks Phillipa

Hi,

I found this report about psychosis with buspirone:

Journal of Psychopharmacology, Vol. 7, No. 3, 295-300 (1993)
DOI: 10.1177/026988119300700311


Acute exacerbation of psychosis with buspirone?
Christos Pantelis
Charing Cross and Westminster Medical School Academic Unit, Horton and Gordon Hospitals, UK

Thomas R. E. Barnes

Charing Cross and Westminster Medical School Academic Unit, Horton and Gordon Hospitals, UK

We report a patient with schizophrenia who suffered an acute exacerbation of psychosis when treated with buspirone to alleviate anxiety. This psychotic reaction appeared to be dose dependent. Discontinuing buspirone resulted in a rapid improvement of psychotic symptoms. Re-introduction of buspirone at a modest dose helped to alleviate anxiety without exacerbating his schizophrenic symptoms. The other case studies of psychosis due to buspirone are reviewed and possible mechanisms for this association are discussed, particularly the role of dopamine and serotonin.

Best regards,
X-ray


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