Posted by Larry Hoover on May 12, 2009, at 6:09:27
In reply to Re: Little more, posted by bleauberry on May 12, 2009, at 5:36:20
I agree that the dose needs to be small enough that there is no real high. The key to that, IMHO, is oral use of standardized products. They can do it with St. John's wort, so why not cannabis?
I'm a user of medicinal marijuana products for a chronic pain condition. Although I can readily obtain bud for smoking, I purchase a product that has been made up analogous to a simple chocolate bar, only instead of cocoa butter, the cook uses cannabis butter. My dosing is something on the order of $.50 to $1.00 worth, and I use that pricing because everything is more or less tied to street pricing. You don't get much pot for 50 cents. From one-half to a full small square of chocolate is all I need, and I generally don't get much of a buzz, if any. But that is the most effective dose. Just as with opiates, the best dose for pain is that amount that just skirts the buzz effect. IMHO. And I use the buzz response as feedback with respect to the amount I chose as my dose. The whole thing is now almost intuitive. With oral preps, moreover, you don't have to deal with any lung injury issues.
FAAH inhibitors might be useful, but then again, they might not. We have no idea what chronic use might do to other inter-related regulatory systems. In other words, the chronic effects might be very different than the acute effects in humans, and we won't know about that from rodent studies.
Lar
poster:Larry Hoover
thread:895287
URL: http://www.dr-bob.org/babble/20090505/msgs/895328.html