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Re: Return to baseline after AD discontinuation bleauberry

Posted by sowhysosad on April 14, 2009, at 9:15:31

In reply to Re: Return to baseline after AD discontinuation, posted by bleauberry on April 14, 2009, at 5:11:27

Yeah, that was my thought too. Two weeks seemed very optimistic!

Perhaps they're allowing a two-week washout to allow the option to use an MAOI, but I sincerely doubt it.

> Well, in this sample of one, after 8 years of prozac and zyprexa I settled into a baseline somewhere in the 3 to 4 month range after the last dose following a slow weaning, where my last dose was about 1/8mg zyprexa and 1mg prozac.
>
> I think all kinds of things have to readjust. Genes that convert proteins to neuros. Receptor sensitivity. Receptor density. Crosstalk between receptors. Cortisol and other hormones. And who knows what. Immune system even. It is a whole body thing, not just as simple as making sure the last molecule of the drug is gone. The bodily adjustments I believe take months, not weeks, and that the previous baseline will never be repeated, because some things were changed permanently.
>
> No proof. Just my intuition.


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