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Re: akathisia + depression is impossible to treat

Posted by sowhysosad on April 13, 2009, at 18:47:05

In reply to Re: akathisia + depression is impossible to treat :[, posted by bleauberry on April 13, 2009, at 17:04:42

> For something really different, you could wait till the end of May and get Savella (Milnacipran). It is new in USA, but has a long track record in the rest of the world as a good one. It is a reuptake inhibitor, 2 parts norepinephrine to 1 part serotonin. I believe that ratio could prevent serotonin induced akathisia, as it would be balanced strongly from the other side. It is kind of like a tricyclic, except without the anticholinergic and other TCA side effects.

Its serotonin reuptake inhibition is much weaker than all the other SSRI's and SNRI's too so it should have a much gentler effect on the 5HT2A/C receptors, assuming that's where the akathisia is coming from.


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URL: http://www.dr-bob.org/babble/20090408/msgs/890429.html