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Mirtazapine use in the UK » manic666

Posted by sowhysosad on April 10, 2009, at 14:18:41

In reply to Re: REMERON 45mg, posted by manic666 on April 6, 2009, at 3:26:59

> yes may be. her is a story from the hospital about mert, it is in the arcives but will tell you ,a girl was brought in , her dad had died 6 months before he was only 40 some thing,she went intoherself an finally snaped ,she was digging in her moms front garden , saying her dad was trying to get out.she was slim an beitiful,they put her on mert an gradualy got a lot better but for the first time in her life put on weight.when well enough to leave she stayed on the mert , but became depressed at the weight gain ,as she was getting married anwanted to look her best , she begged the docs to change her meds , reluctantly they did ,to what i dont no but she is fine now an slim again.so the drug may work well for your friend , she may put on weight but she may not . but if it does an she gets well, the story about the young girl may help ,i think she is looking to have kids now , hers was an illness brought on with her fathers death so she may soon be med free

That's a really encouraging story. I don't doubt that some people's depression is entirely down to low noradrenaline, and for them mirt could work as well if not better than a tricyclic. And I'm sure the sedation and appetite stimulation are life savers for some people too. But for those of us who are suffering low serotonin there's no decent evidence of any serotonergic effect.

Everyone's depression is subtly different, and it seems like some pdocs in the UK use a "one size fits all" approach and pay no attention to how the patient has responded to prior meds.

That was my experience: when I complained about what was clearly norarenaline-related agitation and anxiety on both mirt and a tricyclic, the pdoc's initial solution was to INCREASE the tricyclic dose.

There's an element of Chinese Whisper's involved in my case though. I actually see a junior pdoc who makes extensive notes and then consults with his fully-qualified colleague who makes a decision on what way to go with meds. It's possible some of the relevant information is getting "lost in translation".

Similarly, noradrenergic meds seem to make my chronically depressed friend much worse, and yet the pdoc persists in prescribing them.


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